Expression of NT5C1B-RDH14 in cancer - Summary - The Human Protein Atlas

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NT5C1B-RDH14

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	NT5C1B-RDH14
Gene description	NT5C1B-RDH14 readthrough
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA056683
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA056683

GENE INFORMATION
Gene name	NT5C1B-RDH14
Synonyms
Description	NT5C1B-RDH14 readthrough (HGNC Symbol)
Entrez gene summary	This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase, cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010]
Chromosome	2
Cytoband	p24.2
Chromosome location (bp)	18555545 - 18589564
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000250741 (version 83.38)
Entrez gene	100526794
UniProt
neXtProt
Antibodypedia	NT5C1B-RDH14 antibodies

PROTEIN BROWSER

NT5C1B-RDH14-001	NT5C1B-RDH14-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NT5C1B-RDH14-001 ENSP00000412639 ENST00000444297	C9J2C7 [Direct mapping] Protein NT5C1B-RDH14 Show all	Predicted intracellular proteins Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005737 [cytoplasm] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] GO:0016311 [dephosphorylation] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	533 aa 60.2 kDa	No	0
NT5C1B-RDH14-002 ENSP00000433415 ENST00000532967		Predicted intracellular proteins Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005737 [cytoplasm] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] Show all	602 aa 68 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.