Expression of TMEM200B in cancer - Summary - The Human Protein Atlas

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TMEM200B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM200B
Gene description	Transmembrane protein 200B
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88)
HPA (normal tissue):	Tissue enhanced (endometrium)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA055254
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA055254

GENE INFORMATION
Gene name	TMEM200B (HGNC Symbol)
Synonyms	TTMB
Description	Transmembrane protein 200B (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p35.3
Chromosome location (bp)	29119428 - 29123935
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000253304 (version 83.38)
Entrez gene	399474
UniProt	Q69YZ2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q69YZ2
Antibodypedia	TMEM200B antibodies

PROTEIN BROWSER

TMEM200B-001	TMEM200B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM200B-001 ENSP00000428459 ENST00000521452	Q69YZ2 [Direct mapping] Transmembrane protein 200B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	307 aa 32.7 kDa	No	2
TMEM200B-002 ENSP00000428544 ENST00000420504	Q69YZ2 [Direct mapping] Transmembrane protein 200B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	307 aa 32.7 kDa	No	2

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.