Expression of C1orf210 in cancer - Summary - The Human Protein Atlas

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C1orf210

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C1orf210
Gene description	Chromosome 1 open reading frame 210
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (BEWO, CAPAN-2, T-47d)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expression in selected tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA013788
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA013788

GENE INFORMATION
Gene name	C1orf210 (HGNC Symbol)
Synonyms	MGC52423
Description	Chromosome 1 open reading frame 210 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.2
Chromosome location (bp)	43281883 - 43285617
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000253313 (version 83.38)
Entrez gene	149466
UniProt	Q8IVY1 (UniProt - Inferred from homology)
neXtProt	NX_Q8IVY1
Antibodypedia	C1orf210 antibodies

PROTEIN BROWSER

C1orf210-001	C1orf210-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C1orf210-001 ENSP00000430918 ENST00000523677	Q8IVY1 [Direct mapping] Type III endosome membrane protein TEMP Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0002230 [positive regulation of defense response to virus by host] GO:0005769 [early endosome] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0055037 [recycling endosome] Show all	113 aa 12 kDa	No	1
C1orf210-002 ENSP00000429399 ENST00000423420	Q8IVY1 [Direct mapping] Type III endosome membrane protein TEMP Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0002230 [positive regulation of defense response to virus by host] GO:0005769 [early endosome] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0055037 [recycling endosome] Show all	113 aa 12 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.