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CSNK2A3

GENERAL INFORMATION

Gene name

 CSNK2A3

Gene description

 Casein kinase 2, alpha 3 polypeptide

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (A-431)
HPA (normal tissue):Not detected

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 CSNK2A3 (HGNC Symbol)

Synonyms

 CSNK2A1P

Description

 Casein kinase 2, alpha 3 polypeptide (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that is highly similar to the casein kinase II alpha protein. Casein kinase II is a serine/threonine protein kinase complex that phosphorylates numerous substrates including casein. The alpha subunit is the catalytic component of the complex. Mutations in this gene may be associated with a susceptibility to lung cancer. There are contradictory views among published reports of this gene as to whether or not it is a protein-coding gene or a processed pseudogene (PMIDs: 20625391, 20625391 and 10094393). [provided by RefSeq, Feb 2012]

Chromosome

 11

Cytoband

 p15.4

Chromosome location (bp)

 11351942 - 11353357

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000254598 (version 83.38)

Entrez gene

 283106

UniProt

 Q8NEV1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NEV1

Antibodypedia

 CSNK2A3 antibodies

PROTEIN BROWSER
CSNK2A3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CSNK2A3-001
ENSP00000473553
ENST00000528848
Q8NEV1 [Direct mapping]
Casein kinase II subunit alpha 3
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
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GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
GO:0008284 [positive regulation of cell proliferation]
GO:0030307 [positive regulation of cell growth]
GO:0045732 [positive regulation of protein catabolic process]
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 391 aa
45.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.