Fields »
ABOUT
HELP
BLOG
MPV17L2

GENERAL INFORMATION

Gene name

 MPV17L2

Gene description

 MPV17 mitochondrial membrane protein-like 2

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA043111
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA043111

GENE INFORMATION

Gene name

 MPV17L2 (HGNC Symbol)

Synonyms

 FKSG24, MGC12972

Description

 MPV17 mitochondrial membrane protein-like 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.11

Chromosome location (bp)

 18193182 - 18196948

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000254858 (version 83.38)

Entrez gene

 84769

UniProt

 Q567V2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q567V2

Antibodypedia

 MPV17L2 antibodies

PROTEIN BROWSER
MPV17L2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MPV17L2-001
ENSP00000469836
ENST00000599612
Q567V2 [Direct mapping]
Mpv17-like protein 2
A0A024R7K6 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005762 [mitochondrial large ribosomal subunit]
GO:0016021 [integral component of membrane]
GO:0061668 [mitochondrial ribosome assembly]
GO:0070131 [positive regulation of mitochondrial translation]
Show all
 206 aa
23.2 kDa 		Yes 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.