Expression of BORCS8 in cancer - Summary - The Human Protein Atlas

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BORCS8

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	BORCS8
Gene description	BLOC-1 related complex subunit 8
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Caution, Splice and/or transcript discrepancy exists.
Reliability score	Approved based on 1 antibody. HPA045700
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable).
Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA045700

GENE INFORMATION
Gene name	BORCS8 (HGNC Symbol)
Synonyms	MEF2BNB
Description	BLOC-1 related complex subunit 8 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.11
Chromosome location (bp)	19176903 - 19192591
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000254901 (version 83.38)
Entrez gene	729991
UniProt	Q96FH0 (UniProt - Evidence at protein level)
neXtProt	NX_Q96FH0
Antibodypedia	BORCS8 antibodies

PROTEIN BROWSER

BORCS8-001	BORCS8-007	BORCS8-010	BORCS8-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BORCS8-001 ENSP00000425864 ENST00000462790	Q96FH0 [Direct mapping] Protein MEF2BNB Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0007507 [heart development] Show all	119 aa 13.4 kDa	No	0
BORCS8-007 ENSP00000424833 ENST00000477565	Q96FH0 [Direct mapping] Protein MEF2BNB Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0007507 [heart development] Show all	109 aa 12.5 kDa	No	0
BORCS8-010 ENSP00000467140 ENST00000588208	K7ENY0 [Direct mapping] Protein MEF2BNB Show all	Predicted intracellular proteins Show all		69 aa 7.6 kDa	No	0
BORCS8-013 ENSP00000475370 ENST00000585679	U3KPZ4 [Direct mapping] Protein MEF2BNB Show all	Predicted intracellular proteins Show all		62 aa 6.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.