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ZNF253

GENERAL INFORMATION

Gene name

 ZNF253

Gene description

 Zinc finger protein 253

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at transcript level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), glioma (favourable) and ovarian cancer (favourable).
Renal cancer p<0.001
Glioma p<0.001
Ovarian cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 ZNF253 (HGNC Symbol)

Synonyms

 BMZF-1, FLJ90391, ZNF411

Description

 Zinc finger protein 253 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.11

Chromosome location (bp)

 19865886 - 19894674

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000256771 (version 83.38)

Entrez gene

 56242

UniProt

 O75346 (UniProt - Evidence at transcript level)

neXtProt

 NX_O75346

Antibodypedia

 ZNF253 antibodies

PROTEIN BROWSER
ZNF253-001
ZNF253-002
ZNF253-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF253-001
ENSP00000468720
ENST00000589717
O75346 [Direct mapping]
Zinc finger protein 253
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
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GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0003676 [nucleic acid binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
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 499 aa
57.6 kDa 		No 0
ZNF253-002
ENSP00000347868
ENST00000355650
O75346 [Direct mapping]
Zinc finger protein 253
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
 423 aa
48.7 kDa 		No 0
ZNF253-004
ENSP00000467235
ENST00000592725
K7EP55 [Direct mapping]
Zinc finger protein 253
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Predicted intracellular proteins
Show all
GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
Show all
 215 aa
24.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.