Expression of PRSS58 in cancer - Summary - The Human Protein Atlas

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PRSS58

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	PRSS58
Gene description	Protease, serine, 58
Protein class	Enzymes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	PRSS58 (HGNC Symbol)
Synonyms	TRYX3
Description	Protease, serine, 58 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the trypsin family of serine proteases. This gene and several related trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. This gene was previously described as a trypsinogen-like pseudogene, but it is now thought to be a protein-coding gene. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q34
Chromosome location (bp)	142252143 - 142258058
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000258223 (version 83.38)
Entrez gene	136541
UniProt	Q8IYP2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IYP2
Antibodypedia	PRSS58 antibodies

PROTEIN BROWSER

PRSS58-001	PRSS58-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRSS58-001 ENSP00000447588 ENST00000547058	Q8IYP2 [Direct mapping] Serine protease 58 Show all	Enzymes ENZYME proteins Hydrolases Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0006508 [proteolysis] Show all	241 aa 27.1 kDa	Yes	0
PRSS58-002 ENSP00000446916 ENST00000552471	Q8IYP2 [Direct mapping] Serine protease 58 Show all	Enzymes ENZYME proteins Hydrolases Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0006508 [proteolysis] Show all	241 aa 27.1 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.