Expression of TBC1D3G in cancer - Summary - The Human Protein Atlas

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TBC1D3G

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TBC1D3G
Gene description	TBC1 domain family, member 3G
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 3 antibodies. HPA046969 , HPA047745 , HPA052553
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA046969	HPA047745	HPA052553

GENE INFORMATION
Gene name	TBC1D3G
Synonyms
Description	TBC1 domain family, member 3G (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q12
Chromosome location (bp)	36323884 - 36334759
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000260287 (version 83.38)
Entrez gene	101060321
UniProt	Q6DHY5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6DHY5
Antibodypedia	TBC1D3G antibodies

PROTEIN BROWSER

TBC1D3G-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TBC1D3G-001 ENSP00000456861 ENST00000569055	Q6DHY5 [Direct mapping] TBC1 domain family member 3G Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005096 [GTPase activator activity] GO:0005886 [plasma membrane] GO:0043547 [positive regulation of GTPase activity] Show all	549 aa 62.2 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.