Expression of C16orf95 in cancer - Summary - The Human Protein Atlas

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C16orf95

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C16orf95
Gene description	Chromosome 16 open reading frame 95
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear and nucleolar expression in spermatids and spermatocytes.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 1 antibody. HPA040850
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA040850

Cancer	Cancer staining	Protein expression of normal tissue
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma

Cancer	Cancer staining	Protein expression of normal tissue
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary	One case of carcinoid and subsets of tumor cells in a case of pancreatic cancer displayed strong cytoplasmic staining. A few squamous cell carcinomas were moderately stained. Remaining cancer cells were negative.

GENE INFORMATION
Gene name	C16orf95
Synonyms
Description	Chromosome 16 open reading frame 95 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q24.2
Chromosome location (bp)	87083562 - 87317420
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000260456 (version 83.38)
Entrez gene	100506581
UniProt	Q9H693 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H693
Antibodypedia	C16orf95 antibodies

PROTEIN BROWSER

C16orf95-002	C16orf95-003	C16orf95-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C16orf95-002 ENSP00000253461 ENST00000253461	Q9H693 [Direct mapping] Uncharacterized protein C16orf95 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		158 aa 16.8 kDa	No	0
C16orf95-003 ENSP00000455079 ENST00000567970	H3BNZ7 [Direct mapping] Uncharacterized protein C16orf95 Show all	SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		239 aa 26.5 kDa	No	0
C16orf95-201 ENSP00000484646 ENST00000618367	A0A087X224 [Direct mapping] Uncharacterized protein C16orf95 Show all	Predicted intracellular proteins Show all		143 aa 15.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.