Expression of CLEC19A in cancer - Summary - The Human Protein Atlas

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CLEC19A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CLEC19A
Gene description	C-type lectin domain family 19, member A
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (cerebral cortex)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA042113
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042113

GENE INFORMATION
Gene name	CLEC19A
Synonyms
Description	C-type lectin domain family 19, member A (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p12.3
Chromosome location (bp)	19285739 - 19322145
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000261210 (version 83.38)
Entrez gene
UniProt	Q6UXS0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6UXS0
Antibodypedia	CLEC19A antibodies

PROTEIN BROWSER

CLEC19A-001	CLEC19A-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLEC19A-001 ENSP00000455948 ENST00000465414	Q6UXS0 [Direct mapping] C-type lectin domain family 19 member A Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0030246 [carbohydrate binding] Show all	136 aa 15.4 kDa	Yes	0
CLEC19A-003 ENSP00000455985 ENST00000493231	H3BQX8 [Direct mapping] C-type lectin domain family 19 member A Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		86 aa 9.8 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.