Fields »
ABOUT
HELP
BLOG
TUBB8

GENERAL INFORMATION

Gene name

 TUBB8

Gene description

 Tubulin, beta 8 class VIII

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enriched (testis cancer)
HPA (cell line):Cell line enhanced (MCF7)
HPA (normal tissue):Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene. External characterization data supports antibody staining but no internal RNA data available for correlation.

Reliability score

 Uncertain based on 2 antibodies.
HPA043640 , HPA046280
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enriched (testis cancer)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA043640
HPA046280

GENE INFORMATION

Gene name

 TUBB8 (HGNC Symbol)

Synonyms

 bA631M21.2

Description

 Tubulin, beta 8 class VIII (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

 p15.3

Chromosome location (bp)

 46892 - 74163

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000261456 (version 83.38)

Entrez gene

 347688

UniProt

 Q3ZCM7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q3ZCM7

Antibodypedia

 TUBB8 antibodies

PROTEIN BROWSER
TUBB8-001
TUBB8-002
TUBB8-005
TUBB8-007
TUBB8-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TUBB8-001
ENSP00000456206
ENST00000568584
Q3ZCM7 [Direct mapping]
Tubulin beta-8 chain
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003924 [GTPase activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005525 [GTP binding]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0007017 [microtubule-based process]
GO:0008150 [biological_process]
GO:0008152 [metabolic process]
GO:0043234 [protein complex]
GO:0051258 [protein polymerization]
GO:0070062 [extracellular exosome]
Show all
 444 aa
49.8 kDa 		No 0
TUBB8-002
ENSP00000456899
ENST00000562809
A0A075B735 [Direct mapping]
Tubulin beta-8 chain
Show all
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0008152 [metabolic process]
Show all
 75 aa
7.8 kDa 		No 0
TUBB8-005
ENSP00000457610
ENST00000564130
Q5SQY0 [Direct mapping]
Tubulin beta-8 chain; Tubulin, beta 8, isoform CRA_c
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005525 [GTP binding]
GO:0005874 [microtubule]
GO:0007017 [microtubule-based process]
GO:0008152 [metabolic process]
GO:0043234 [protein complex]
GO:0051258 [protein polymerization]
Show all
 410 aa
45.5 kDa 		No 0
TUBB8-007
ENSP00000454878
ENST00000561967
A0A075B724 [Direct mapping]
Tubulin beta-8 chain
Show all
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005525 [GTP binding]
GO:0005874 [microtubule]
GO:0007017 [microtubule-based process]
GO:0008152 [metabolic process]
Show all
 119 aa
13 kDa 		No 0
TUBB8-008
ENSP00000457062
ENST00000568866
A0A075B736 [Direct mapping]
Tubulin beta-8 chain
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005525 [GTP binding]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0007017 [microtubule-based process]
GO:0008152 [metabolic process]
GO:0043234 [protein complex]
GO:0051258 [protein polymerization]
Show all
 407 aa
45.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.