Expression of ISY1-RAB43 in cancer - Summary - The Human Protein Atlas

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ISY1-RAB43

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ISY1-RAB43
Gene description	ISY1-RAB43 readthrough
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous nuclear and nuclear membranous expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Approved based on 2 antibodies. HPA006312 , HPA016995
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA006312	HPA016995

GENE INFORMATION
Gene name	ISY1-RAB43
Synonyms
Description	ISY1-RAB43 readthrough (HGNC Symbol)
Entrez gene summary	This locus represents naturally occurring read-through transcription between the neighboring ISY1 (ISY1 splicing factor homolog) and RAB43 (RAB43, member RAS oncogene family) gene on chromosome 3. The read-through transcript encodes a protein that shares sequence identity with the upstream gene product, but its C-terminus is distinct due to a frameshift relative to the downstream gene. [provided by RefSeq, Mar 2011]
Chromosome	3
Cytoband	q21.3
Chromosome location (bp)	129087575 - 129161036
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000261796 (version 83.38)
Entrez gene	100534599
UniProt
neXtProt
Antibodypedia	ISY1-RAB43 antibodies

PROTEIN BROWSER

ISY1-RAB43-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ISY1-RAB43-001 ENSP00000411822 ENST00000418265		Predicted intracellular proteins Show all		331 aa 37.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.