Expression of PPIAL4A in cancer - Summary - The Human Protein Atlas

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PPIAL4A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PPIAL4A
Gene description	Peptidylprolyl isomerase A (cyclophilin A)-like 4A
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Mixed
HPA (normal tissue):	Not detected

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA058345
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA058345

GENE INFORMATION
Gene name	PPIAL4A (HGNC Symbol)
Synonyms	COAS2, PPIAL4, PPIAL4B
Description	Peptidylprolyl isomerase A (cyclophilin A)-like 4A (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p11.2
Chromosome location (bp)	120889746 - 120890405
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000263353 (version 83.38)
Entrez gene	653505
UniProt	Q9Y536 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y536
Antibodypedia	PPIAL4A antibodies

PROTEIN BROWSER

PPIAL4A-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPIAL4A-002 ENSP00000485206 ENST00000577856	Q9Y536 [Direct mapping] Peptidyl-prolyl cis-trans isomerase A-like 4A Show all	Enzymes ENZYME proteins Isomerase Predicted intracellular proteins Show all	GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0005737 [cytoplasm] GO:0006457 [protein folding] GO:0070062 [extracellular exosome] Show all	164 aa 18.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.