Cell atlas - DYNLL2 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	DYNLL2
Gene description	Dynein, light chain, LC8-type 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol & nucleoplasm. In addition localized to the nuclear bodies. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (uncertain), Cytosol (uncertain)
Additional location	In addition localized to the Nuclear bodies (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA039954
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol & nucleoplasm. In addition localized to the nuclear bodies. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nucleoplasm (uncertain), Cytosol (uncertain)

Additional location

Nuclear bodies (uncertain)


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Antibody	Cell line	Location
HPA039954	MCF7	Nucleoplasm
HPA039954	MCF7	Cytosol
HPA039954	PC-3	Nucleoplasm
		Nuclear bodies
		Cytosol
HPA039954	U-2 OS	Nucleoplasm
HPA039954	U-2 OS	Cytosol

GENE INFORMATION
Gene name	DYNLL2 (HGNC Symbol)
Synonyms	Dlc2, DNCL1B, MGC17810, RSPH22
Description	Dynein, light chain, LC8-type 2 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q22
Chromosome location (bp)	58083415 - 58095536
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000264364 (version 83.38)
Entrez gene	140735
UniProt	Q96FJ2 (UniProt - Evidence at protein level)
neXtProt	NX_Q96FJ2
Antibodypedia	DYNLL2 antibodies

PROTEIN BROWSER

DYNLL2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DYNLL2-001 ENSP00000477310 ENST00000579991	Q96FJ2 [Direct mapping] Dynein light chain 2, cytoplasmic Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003774 [motor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005829 [cytosol] GO:0005874 [microtubule] GO:0005875 [microtubule associated complex] GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0006915 [apoptotic process] GO:0006996 [organelle organization] GO:0007017 [microtubule-based process] GO:0008039 [synaptic target recognition] GO:0008092 [cytoskeletal protein binding] GO:0012501 [programmed cell death] GO:0016020 [membrane] GO:0016236 [macroautophagy] GO:0016459 [myosin complex] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030286 [dynein complex] GO:0072372 [primary cilium] GO:0097193 [intrinsic apoptotic signaling pathway] GO:0097542 [ciliary tip] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] Show all	89 aa 10.3 kDa	No	0