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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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AC011513.3
  • TISSUE

  • CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

AC011513.3

Gene description

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Tissue enhanced (stomach cancer)
HPA (cell line):Not detected
HPA (normal tissue):Group enriched (colon, esophagus)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in several tissue types, most abundant in gastrointestinal tract.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.

Reliability score

Approved based on 1 antibody.
HPA011041
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Tissue enhanced (stomach cancer)

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA011041

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most malignant tissues were negative or showed occasional weak to moderate cytoplasmic and membranous immunoreactivity. Some tumors showed a granular staining pattern. A few lung cancers were stronger stained.

GENE INFORMATION

Gene name

AC011513.3

Synonyms

Description

Entrez gene summary

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

41708612 - 41761282

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000267881 (version 83.38)

Entrez gene

UniProt

neXtProt

Antibodypedia

AC011513.3 antibodies

PROTEIN BROWSER

AC011513.3-001
AC011513.3-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AC011513.3-001
ENSP00000469421
ENST00000598976
M0QXV9 [Direct mapping]
Uncharacterized protein
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
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GO:0005515 [protein binding]
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152 aa
17.1 kDa
Yes 0
AC011513.3-002
ENSP00000469926
ENST00000435837
M0QYM2 [Direct mapping]
Uncharacterized protein
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
67 aa
7.6 kDa
Yes 0

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The Human Protein Atlas project is funded
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