Expression of CTAG1A in cancer - Summary - The Human Protein Atlas

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CTAG1A

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CTAG1A
Gene description	Cancer/testis antigen 1A
Protein class	Cancer-related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Group enriched (U-266/70, U-266/84)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct cytoplasmic expression in spermatocytes.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. CAB013061
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

CAB013061

GENE INFORMATION
Gene name	CTAG1A (HGNC Symbol)
Synonyms	ESO1, LAGE2A
Description	Cancer/testis antigen 1A (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome. [provided by RefSeq, Dec 2015]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	154585143 - 154586821
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000268651 (version 83.38)
Entrez gene	246100
UniProt	P78358 (UniProt - Evidence at protein level)
neXtProt	NX_P78358
Antibodypedia	CTAG1A antibodies

PROTEIN BROWSER

CTAG1A-002	CTAG1A-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CTAG1A-002 ENSP00000469441 ENST00000599837	P78358 [Direct mapping] Cancer/testis antigen 1 Show all	Phobius predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	180 aa 18 kDa	No	0
CTAG1A-201 ENSP00000472220 ENST00000593606	A0A0A0MTT5 [Direct mapping] Cancer/testis antigen 1 Show all	Predicted intracellular proteins Show all		210 aa 20.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.