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TRABD2B

GENERAL INFORMATION

Gene name

 TRABD2B

Gene description

 TraB domain containing 2B

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enriched (renal cancer)
HPA (cell line):Group enriched (HeLa, U-2197)
HPA (normal tissue):Tissue enhanced (kidney)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 1 antibody.
HPA045817
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enriched (renal cancer)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA045817

GENE INFORMATION

Gene name

 TRABD2B (HGNC Symbol)

Synonyms

 TIKI2

Description

 TraB domain containing 2B (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p33

Chromosome location (bp)

 47760528 - 47996895

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000269113 (version 83.38)

Entrez gene

 388630

UniProt

 A6NFA1 (UniProt - Evidence at protein level)

neXtProt

 NX_A6NFA1

Antibodypedia

 TRABD2B antibodies

PROTEIN BROWSER
TRABD2B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRABD2B-001
ENSP00000476820
ENST00000606738
A6NFA1 [Direct mapping]
Metalloprotease TIKI2
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   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
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GO:0004222 [metalloendopeptidase activity]
GO:0005515 [protein binding]
GO:0005887 [integral component of plasma membrane]
GO:0006508 [proteolysis]
GO:0008152 [metabolic process]
GO:0016055 [Wnt signaling pathway]
GO:0017147 [Wnt-protein binding]
GO:0018158 [protein oxidation]
GO:0030178 [negative regulation of Wnt signaling pathway]
GO:0031301 [integral component of organelle membrane]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
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 517 aa
57.4 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.