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ZNF587B

GENERAL INFORMATION

Gene name

 ZNF587B

Gene description

 Zinc finger protein 587B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 2 antibodies.
HPA043800 , HPA053762
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PROGNOSTIC SUMMARY
Prognostic marker in prostate cancer (unfavourable) and melanoma (unfavourable).
Prostate cancer p<0.001
Melanoma p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA043800
HPA053762

GENE INFORMATION

Gene name

 ZNF587B

Synonyms

Description

 Zinc finger protein 587B (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 q13.43

Chromosome location (bp)

 57819741 - 57846238

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000269343 (version 83.38)

Entrez gene

 100293516

UniProt

 E7ETH6 (UniProt - Evidence at protein level)

neXtProt

 NX_E7ETH6

Antibodypedia

 ZNF587B antibodies

PROTEIN BROWSER
ZNF587B-001
ZNF587B-002
ZNF587B-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF587B-001
ENSP00000392410
ENST00000442832
E7ETH6 [Direct mapping]
Zinc finger protein 587B
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Predicted intracellular proteins
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GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
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 402 aa
45.5 kDa 		No 0
ZNF587B-002
ENSP00000469623
ENST00000594901
M0QY62 [Direct mapping]
Zinc finger protein 587B
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Predicted intracellular proteins
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GO:0003676 [nucleic acid binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
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 633 aa
72.2 kDa 		No 0
ZNF587B-003
ENSP00000472004
ENST00000594328
M0R1N2 [Direct mapping]
Zinc finger protein 587B
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Predicted intracellular proteins
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GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
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 432 aa
49.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.