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DMRTC1

GENERAL INFORMATION

Gene name

 DMRTC1

Gene description

 DMRT-like family C1

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Tissue enhanced (cerebral cortex)

Protein evidence

 Evidence at transcript level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 2 antibodies.
HPA046874 , HPA046992
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA046874
HPA046992

GENE INFORMATION

Gene name

 DMRTC1

Synonyms

Description

 DMRT-like family C1 (HGNC Symbol)

Entrez gene summary

Chromosome

 X

Cytoband

 q13.1

Chromosome location (bp)

 72872025 - 72943814

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000269502 (version 83.38)

Entrez gene

 63947

UniProt

 Q5HYR2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q5HYR2

Antibodypedia

 DMRTC1 antibodies

PROTEIN BROWSER
DMRTC1-002
DMRTC1-003
DMRTC1-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DMRTC1-002
ENSP00000469615
ENST00000596389
Q5HYR2 [Direct mapping]
Doublesex- and mab-3-related transcription factor C1
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
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GO:0000987 [core promoter proximal region sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007548 [sex differentiation]
GO:0042803 [protein homodimerization activity]
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 127 aa
13.5 kDa 		No 0
DMRTC1-003
ENSP00000471224
ENST00000595412
Q5HYR2 [Direct mapping]
Doublesex- and mab-3-related transcription factor C1
A0A024R4F7 [Target identity:100%; Query identity:100%]
HCG1731871, isoform CRA_b
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000987 [core promoter proximal region sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007548 [sex differentiation]
GO:0042803 [protein homodimerization activity]
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 192 aa
20.1 kDa 		No 0
DMRTC1-004
ENSP00000484718
ENST00000615063
A0A087X258 [Direct mapping]
Doublesex- and mab-3-related transcription factor C1
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Predicted intracellular proteins
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GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
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 139 aa
14.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.