Expression of FAM25C in cancer - Summary - The Human Protein Atlas

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FAM25C

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM25C
Gene description	Family with sequence similarity 25, member C
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (head and neck cancer)
HPA (cell line):	Cell line enriched (SK-BR-3)
HPA (normal tissue):	Group enriched (breast, esophagus, skin, small intestine, tonsil)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA044808
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (head and neck cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044808

GENE INFORMATION
Gene name	FAM25C (HGNC Symbol)
Synonyms	bA164N7.4
Description	Family with sequence similarity 25, member C (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q11.22
Chromosome location (bp)	47995355 - 47999791
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000276430 (version 83.38)
Entrez gene	644054
UniProt	B3EWG5 (UniProt - Inferred from homology,UniProt - Uncertain), B3EWG4 (UniProt - Inferred from homology,UniProt - Uncertain)
neXtProt	NX_B3EWG5, NX_B3EWG4
Antibodypedia	FAM25C antibodies

PROTEIN BROWSER

FAM25C-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM25C-001 ENSP00000485370 ENST00000617224	B3EWG5 [Direct mapping] Protein FAM25C B3EWG4 [Target identity:100%; Query identity:100%] Putative protein FAM25BP Show all	Predicted intracellular proteins Show all		89 aa 9.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.