Expression of RP4-608O15.3 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

RP4-608O15.3

premium

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RP4-608O15.3
Gene description	Complement factor H-related protein 2
Protein class	Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (liver)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct positivity in plasma, extracellular matrix and proximal renal tubules.

ANTIBODY IHC RELIABILITY
Data reliability description	Caution, targets protein from more than one gene. Secreted protein, tissue location of RNA and protein might differ and correlation is complex. Antibody staining in cells/structures not annotated, view images.
Reliability score	Supported based on 3 antibodies. HPA038915 , HPA040726 , HPA049813
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038915	HPA040726	HPA049813

GENE INFORMATION
Gene name	RP4-608O15.3
Synonyms
Description	Complement factor H-related protein 2 (UniProtKB/Swiss-Prot)
Entrez gene summary
Chromosome	1
Cytoband	q31.3
Chromosome location (bp)	196819745 - 196959210
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000276911 (version 83.38)
Entrez gene
UniProt	P36980 (UniProt - Evidence at protein level)
neXtProt	NX_P36980
Antibodypedia	RP4-608O15.3 antibodies

PROTEIN BROWSER

RP4-608O15.3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RP4-608O15.3-001 ENSP00000356391 ENST00000367421	P36980 [Direct mapping] Complement factor H-related protein 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Show all	GO:0005576 [extracellular region] Show all	270 aa 30.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.