Expression of ABC7-42404400C24.1 in cancer - Summary - The Human Protein Atlas

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ABC7-42404400C24.1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABC7-42404400C24.1
Gene description
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (SK-BR-3)
HPA (normal tissue):	Tissue enhanced (cerebral cortex, lung)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Mainly nuclear expression in cerebral cortex.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Approved based on 2 antibodies. HPA036971 , HPA036972
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036971	HPA036972

GENE INFORMATION
Gene name	ABC7-42404400C24.1
Synonyms
Description
Entrez gene summary
Chromosome	10
Cytoband	q11.22
Chromosome location (bp)	47750864 - 47763592
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000277758 (version 83.38)
Entrez gene	102724488
UniProt
neXtProt
Antibodypedia	ABC7-42404400C24.1 antibodies

PROTEIN BROWSER

ABC7-42404400C24.1-001	ABC7-42404400C24.1-004	ABC7-42404400C24.1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABC7-42404400C24.1-001 ENSP00000485217 ENST00000623662	X6R8R1 [Direct mapping] Synaptotagmin-15 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005886 [plasma membrane] GO:0016079 [synaptic vesicle exocytosis] GO:0017158 [regulation of calcium ion-dependent exocytosis] GO:0019905 [syntaxin binding] GO:0030276 [clathrin binding] GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter] Show all	474 aa 52.2 kDa	No	0
ABC7-42404400C24.1-004 ENSP00000478933 ENST00000615923	A0A096LNH4 [Direct mapping] Synaptotagmin-15 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	444 aa 49.6 kDa	No	1
ABC7-42404400C24.1-201 ENSP00000482225 ENST00000622861		Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] Show all	390 aa 43.5 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.