Expression of CT45A8 in cancer - Summary - The Human Protein Atlas

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CT45A8

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CT45A8
Gene description	Cancer/testis antigen family 45, member A8
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Group enriched (AN3-CA, HMC-1)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in testis of seminiferus ducts.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 4 antibodies. HPA044735 , HPA044757 , HPA046872 , HPA046987
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044735	HPA044757	HPA046872	HPA046987

GENE INFORMATION
Gene name	CT45A8
Synonyms
Description	Cancer/testis antigen family 45, member A8 (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	q26.3
Chromosome location (bp)	135846499 - 135854538
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000278085 (version 83.38)
Entrez gene	102723737
UniProt	P0DMV1 (UniProt - Inferred from homology)
neXtProt	NX_P0DMV1
Antibodypedia	CT45A8 antibodies

PROTEIN BROWSER

CT45A8-001	CT45A8-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CT45A8-001 ENSP00000481184 ENST00000611660	P0DMV1 [Direct mapping] Cancer/testis antigen family 45 member A8 Show all	Predicted intracellular proteins Show all		189 aa 21.4 kDa	No	0
CT45A8-201 ENSP00000480644 ENST00000611438	P0DMV1 [Direct mapping] Cancer/testis antigen family 45 member A8 Show all	Predicted intracellular proteins Show all		189 aa 21.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.