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PCDH20

GENERAL INFORMATION

Gene name

 PCDH20

Gene description

 Protocadherin 20

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Cell line enriched (RPTEC TERT1)
HPA (normal tissue):Tissue enhanced (cerebral cortex, smooth muscle)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 PCDH20 (HGNC Symbol)

Synonyms

 FLJ22218, PCDH13

Description

 Protocadherin 20 (HGNC Symbol)

Entrez gene summary

 This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq, Jul 2008]

Chromosome

 13

Cytoband

 q21.2

Chromosome location (bp)

 61409685 - 61415522

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000280165 (version 83.38)

Entrez gene

 64881

UniProt

 Q8N6Y1 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8N6Y1

Antibodypedia

 PCDH20 antibodies

PROTEIN BROWSER
PCDH20-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PCDH20-001
ENSP00000387250
ENST00000409204
Q8N6Y1 [Direct mapping]
Protocadherin-20
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
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GO:0005509 [calcium ion binding]
GO:0005886 [plasma membrane]
GO:0007155 [cell adhesion]
GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0044822 [poly(A) RNA binding]
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 951 aa
104.9 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.