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Staining of nuclear speckles in human cell line HaCaT (HPA070713)
Scale bar represents 10µm
Nuclear speckles
Nuclear speckles are a non-membrane-bound nuclear sub-compartment that contains pre-mRNA splicing factors. Besides the storage of those splicing factors nuclear speckles are thought to serve as a regulatory site for transcription.
Immunofluorescent staining
Nuclear speckles appear as an irregular, mottled staining pattern inside the nucleoplasm.
