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ZMYND10

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GENERAL INFORMATION

Gene name

 ZMYND10

Gene description

 Zinc finger, MYND-type containing 10

Protein class

 Disease related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the plasma membrane & cytosol.

RNA cell category

 Cell line enhanced (T-47d, U-87 MG)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Plasma membrane (approved), Cytosol (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA035255
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (T-47d, U-87 MG)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the plasma membrane & cytosol.

Main location

 Plasma membrane (approved), Cytosol (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA035255 A-431 Plasma membrane
Cytosol
HPA035255 U-2 OS Plasma membrane
Cytosol
HPA035255 U-251 MG Plasma membrane
Cytosol

GENE INFORMATION

Gene name

 ZMYND10 (HGNC Symbol)

Synonyms

 BLU, CILD22

Description

 Zinc finger, MYND-type containing 10 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein containing a MYND-type zinc finger domain that likely functions in assembly of the dynein motor. Mutations in this gene can cause primary ciliary dyskinesia. This gene is also considered a tumor suppressor gene and is often mutated, deleted, or hypermethylated and silenced in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Chromosome

 3

Cytoband

 p21.31

Chromosome location (bp)

 50341110 - 50346852

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000004838 (version 83.38)

Entrez gene

 51364

UniProt

 O75800 (UniProt - Evidence at protein level)

neXtProt

 NX_O75800

Antibodypedia

 ZMYND10 antibodies

PROTEIN BROWSER
ZMYND10-001
ZMYND10-002
ZMYND10-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZMYND10-001
ENSP00000231749
ENST00000231749
O75800 [Direct mapping]
Zinc finger MYND domain-containing protein 10
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Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0034451 [centriolar satellite]
GO:0036158 [outer dynein arm assembly]
GO:0036159 [inner dynein arm assembly]
GO:0044458 [motile cilium assembly]
GO:0046872 [metal ion binding]
Show all
 440 aa
50.3 kDa 		No 0
ZMYND10-002
ENSP00000353289
ENST00000360165
O75800 [Direct mapping]
Zinc finger MYND domain-containing protein 10
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Predicted intracellular proteins
Plasma proteins
Disease related genes
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0034451 [centriolar satellite]
GO:0036158 [outer dynein arm assembly]
GO:0036159 [inner dynein arm assembly]
GO:0044458 [motile cilium assembly]
GO:0046872 [metal ion binding]
Show all
 435 aa
50 kDa 		No 0
ZMYND10-003
ENSP00000393687
ENST00000442887
C9JUQ8 [Direct mapping]
Zinc finger MYND domain-containing protein 10
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Predicted intracellular proteins
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 282 aa
31.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.