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RNA cell line category: Cell line enriched (SK-MEL-30)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
GENE INFORMATION
Gene name
ABCB5 (HGNC Symbol)
Synonyms
ABCB5alpha, ABCB5beta, EST422562
Description
ATP-binding cassette, sub-family B (MDR/TAP), member 5 (HGNC Symbol)
Entrez gene summary
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
Q2M3G0 [Direct mapping] ATP-binding cassette sub-family B member 5
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Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014)
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GO:0002481 [antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent] GO:0002485 [antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent] GO:0002489 [antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent] GO:0002591 [positive regulation of antigen processing and presentation of peptide antigen via MHC class I] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006810 [transport] GO:0008152 [metabolic process] GO:0015562 [efflux transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0016887 [ATPase activity] GO:0030154 [cell differentiation] GO:0042391 [regulation of membrane potential] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0048058 [compound eye corneal lens development] GO:0055085 [transmembrane transport]
Q2M3G0 [Direct mapping] ATP-binding cassette sub-family B member 5
Show all
Transporters Primary Active Transporters Predicted intracellular proteins
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GO:0002481 [antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent] GO:0002485 [antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent] GO:0002489 [antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent] GO:0002591 [positive regulation of antigen processing and presentation of peptide antigen via MHC class I] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0008152 [metabolic process] GO:0015562 [efflux transmembrane transporter activity] GO:0016887 [ATPase activity] GO:0030154 [cell differentiation] GO:0042391 [regulation of membrane potential] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0048058 [compound eye corneal lens development] GO:0055085 [transmembrane transport]
Q2M3G0 [Direct mapping] ATP-binding cassette sub-family B member 5 A0A024RA03 [Target identity:100%; Query identity:100%] HCG38926, isoform CRA_a
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Transporters Primary Active Transporters Predicted intracellular proteins
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GO:0002481 [antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent] GO:0002485 [antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent] GO:0002489 [antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent] GO:0002591 [positive regulation of antigen processing and presentation of peptide antigen via MHC class I] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0008152 [metabolic process] GO:0015562 [efflux transmembrane transporter activity] GO:0016887 [ATPase activity] GO:0030154 [cell differentiation] GO:0042391 [regulation of membrane potential] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0048058 [compound eye corneal lens development] GO:0055085 [transmembrane transport]
Q2M3G0 [Direct mapping] ATP-binding cassette sub-family B member 5
Show all
Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014)
Show all
GO:0002481 [antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent] GO:0002485 [antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent] GO:0002489 [antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent] GO:0002591 [positive regulation of antigen processing and presentation of peptide antigen via MHC class I] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006810 [transport] GO:0008152 [metabolic process] GO:0015562 [efflux transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0016887 [ATPase activity] GO:0030154 [cell differentiation] GO:0042391 [regulation of membrane potential] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0048058 [compound eye corneal lens development] GO:0055085 [transmembrane transport]
