Expression of AC004381.6 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

AC004381.6

premium

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	AC004381.6
Gene description	Putative RNA exonuclease NEF-sp
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	12
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 2 antibodies. HPA040755 , HPA040868
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA040755	HPA040868

GENE INFORMATION
Gene name	AC004381.6
Synonyms
Description	Putative RNA exonuclease NEF-sp (UniProtKB/Swiss-Prot)
Entrez gene summary
Chromosome	16
Cytoband	p12.3
Chromosome location (bp)	20806429 - 20849668
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000005189 (version 83.38)
Entrez gene	81691
UniProt	Q96IC2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96IC2
Antibodypedia	AC004381.6 antibodies

PROTEIN BROWSER

AC004381.6-001	AC004381.6-003	AC004381.6-004	AC004381.6-006	AC004381.6-007	AC004381.6-008	AC004381.6-009	AC004381.6-010	AC004381.6-011	AC004381.6-012	AC004381.6-013	AC004381.6-020

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AC004381.6-001 ENSP00000261377 ENST00000261377	Q96IC2 [Target identity:100%; Query identity:100%] Putative RNA exonuclease NEF-sp A0A024R390 [Target identity:100%; Query identity:100%] Exonuclease NEF-sp, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0004527 [exonuclease activity] GO:0005730 [nucleolus] GO:0070062 [extracellular exosome] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	774 aa 86.9 kDa	No	0
AC004381.6-003 ENSP00000261378 ENST00000348433		Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	743 aa 83.5 kDa	No	0
AC004381.6-004 ENSP00000457616 ENST00000564274	Q96IC2 [Target identity:100%; Query identity:100%] Putative RNA exonuclease NEF-sp A0A024R390 [Target identity:100%; Query identity:100%] Exonuclease NEF-sp, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0004527 [exonuclease activity] GO:0005730 [nucleolus] GO:0070062 [extracellular exosome] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	774 aa 86.9 kDa	No	0
AC004381.6-006 ENSP00000457789 ENST00000568894	H3BUT7 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		172 aa 19.6 kDa	No	0
AC004381.6-007 ENSP00000455233 ENST00000568046	H3BPB2 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		102 aa 11.6 kDa	No	0
AC004381.6-008 ENSP00000456666 ENST00000563068	H3BSE4 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		105 aa 12 kDa	No	0
AC004381.6-009 ENSP00000456643 ENST00000568501	H3BSC5 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		78 aa 8.9 kDa	No	0
AC004381.6-010 ENSP00000456030 ENST00000568647	H3BR13 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		162 aa 18.5 kDa	No	0
AC004381.6-011 ENSP00000455677 ENST00000565340	H3BQ98 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	143 aa 16.3 kDa	No	0
AC004381.6-012 ENSP00000454262 ENST00000566276	H3BM72 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	212 aa 23.7 kDa	No	0
AC004381.6-013 ENSP00000458004 ENST00000563617	H3BV93 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		144 aa 16.3 kDa	No	0
AC004381.6-020 ENSP00000455867 ENST00000561474	H3BQP3 [Direct mapping] Protein LOC81691 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] Show all	206 aa 22.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.