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COPZ2

GENERAL INFORMATION

Gene name

 COPZ2

Gene description

 Coatomer protein complex, subunit zeta 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues at variable levels.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA055999
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 COPZ2 (HGNC Symbol)

Synonyms

 MGC23008

Description

 Coatomer protein complex, subunit zeta 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the adaptor complexes small subunit family. The encoded protein is a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. [provided by RefSeq, Feb 2014]

Chromosome

 17

Cytoband

 q21.32

Chromosome location (bp)

 48026167 - 48038030

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000005243 (version 83.38)

Entrez gene

 51226

UniProt

 Q9P299 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9P299

Antibodypedia

 COPZ2 antibodies

PROTEIN BROWSER
COPZ2-001
COPZ2-002
COPZ2-003
COPZ2-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
COPZ2-001
ENSP00000480707
ENST00000621465
Q9P299 [Direct mapping]
Coatomer subunit zeta-2
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   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005801 [cis-Golgi network]
GO:0006810 [transport]
GO:0006886 [intracellular protein transport]
GO:0016192 [vesicle-mediated transport]
GO:0030126 [COPI vesicle coat]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
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 210 aa
23.5 kDa 		No 0
COPZ2-002
ENSP00000463581
ENST00000580174
A0A0G2JLH9 [Direct mapping]
Coatomer subunit zeta-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 9 aa
1.2 kDa 		No 0
COPZ2-003
ENSP00000462035
ENST00000581756
J3KRJ9 [Direct mapping]
Coatomer subunit zeta-2
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006810 [transport]
GO:0015031 [protein transport]
Show all
 141 aa
16 kDa 		No 0
COPZ2-006
ENSP00000463841
ENST00000579263
J3QQQ5 [Direct mapping]
Coatomer subunit zeta-2
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   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006810 [transport]
GO:0015031 [protein transport]
Show all
 79 aa
9.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.