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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

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Cell type

Expression

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Specificity

Cell line

Specificity

Cancer

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Tissue

Detectable

Cell line

Detectable

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Detectable

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Antibodies

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KRT33A
  • TISSUE

  • CELL

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

KRT33A

Gene description

Keratin 33A, type I

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Group enriched (esophagus, testis)
GTEx:Tissue enriched (skin)
FANTOM5:Not detected

Protein evidence

Evidence at protein level

Protein expression

Highly expressed in hair follicle cortex.

DATA RELIABILITY

Data reliability
description

Antibody staining consistent with RNA expression data. Caution, targets protein from more than one gene. External characterization data supports antibody staining.

Reliability score

Supported based on 1 antibody.
HPA055194
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Hair
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Hair

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (esophagus, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skin)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected

GENE INFORMATION

Gene name

KRT33A (HGNC Symbol)

Synonyms

Ha-3I, Krt1-3, KRTHA3A

Description

Keratin 33A, type I (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the keratin gene family. This gene is one of multiple type I hair keratin genes that are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, the encoded protein is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, keratin 33A and keratin 33B. [provided by RefSeq, May 2012]

Chromosome

17

Cytoband

q21.2

Chromosome location (bp)

41346092 - 41350812

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006059 (version 83.38)

Entrez gene

3883

UniProt

O76009 (UniProt - Evidence at transcript level)

neXtProt

NX_O76009

Antibodypedia

KRT33A antibodies

PROTEIN BROWSER

KRT33A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KRT33A-001
ENSP00000007735
ENST00000007735
O76009 [Direct mapping]
Keratin, type I cuticular Ha3-I
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005198 [structural molecule activity]
GO:0005615 [extracellular space]
GO:0005882 [intermediate filament]
Show all
404 aa
45.9 kDa
No 0

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