Expression of CACNA1G in cancer - Summary

GENERAL INFORMATION
Gene name	CACNA1G
Gene description	Calcium channel, voltage-dependent, T type, alpha 1G subunit
Protein class	FDA approved drug targets Plasma proteins Predicted membrane proteins Voltage-gated ion channels
Predicted localization	Membrane
Number of transcripts	28
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (A549)
HPA (normal tissue):	Tissue enhanced (cerebral cortex, cervix, uterine)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results.
Reliability score	Uncertain based on 1 antibody. HPA004714
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

STAINING SUMMARY

HPA004714

GENE INFORMATION
Gene name	CACNA1G (HGNC Symbol)
Synonyms	Cav3.1, NBR13
Description	Calcium channel, voltage-dependent, T type, alpha 1G subunit (HGNC Symbol)
Entrez gene summary	Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]
Chromosome	17
Cytoband	q21.33
Chromosome location (bp)	50561068 - 50627474
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006283 (version 83.38)
Entrez gene	8913
UniProt	O43497 (UniProt - Evidence at transcript level)
neXtProt	NX_O43497
Antibodypedia	CACNA1G antibodies

PROTEIN BROWSER

CACNA1G-001	CACNA1G-002	CACNA1G-003	CACNA1G-004	CACNA1G-005	CACNA1G-007	CACNA1G-008	CACNA1G-009	CACNA1G-011	CACNA1G-013	CACNA1G-015	CACNA1G-016	CACNA1G-018	CACNA1G-019	CACNA1G-020	CACNA1G-021	CACNA1G-023	CACNA1G-024	CACNA1G-025	CACNA1G-026	CACNA1G-027	CACNA1G-028	CACNA1G-029	CACNA1G-031	CACNA1G-032	CACNA1G-034	CACNA1G-035	CACNA1G-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CACNA1G-001 ENSP00000339302 ENST00000352832	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2250 aa 249.3 kDa	No	>9
CACNA1G-002 ENSP00000425451 ENST00000513964	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2239 aa 247.8 kDa	No	>9
CACNA1G-003 ENSP00000422407 ENST00000514717	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2227 aa 246.2 kDa	No	>9
CACNA1G-004 ENSP00000426814 ENST00000510366	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2232 aa 247 kDa	No	>9
CACNA1G-005 ENSP00000427238 ENST00000503485	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2250 aa 248.7 kDa	No	>9
CACNA1G-007 ENSP00000414388 ENST00000429973	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2266 aa 251 kDa	No	>9
CACNA1G-008 ENSP00000353990 ENST00000360761	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2261 aa 250.2 kDa	No	>9
CACNA1G-009 ENSP00000423112 ENST00000507510	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2332 aa 257.7 kDa	No	>9
CACNA1G-011 ENSP00000420918 ENST00000507336	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2366 aa 261.6 kDa	No	>9
CACNA1G-013 ENSP00000352011 ENST00000359106	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0001508 [action potential] GO:0002027 [regulation of heart rate] GO:0005216 [ion channel activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007268 [synaptic transmission] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0010045 [response to nickel cation] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0060371 [regulation of atrial cardiac muscle cell membrane depolarization] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2377 aa 262.5 kDa	No	>9
CACNA1G-015 ENSP00000426172 ENST00000513689	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2287 aa 252.8 kDa	No	>9
CACNA1G-016 ENSP00000423045 ENST00000507609	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2277 aa 251.9 kDa	No	>9
CACNA1G-018 ENSP00000427173 ENST00000510115	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2298 aa 254.4 kDa	No	>9
CACNA1G-019 ENSP00000409759 ENST00000442258	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2243 aa 248.5 kDa	No	>9
CACNA1G-020 ENSP00000426098 ENST00000515165	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2284 aa 252.7 kDa	No	>9
CACNA1G-021 ENSP00000425698 ENST00000514181	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2259 aa 250.2 kDa	No	>9
CACNA1G-023 ENSP00000392390 ENST00000416767	A0A0B4J1X2 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006811 [ion transport] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] Show all	1555 aa 171.4 kDa	No	>9
CACNA1G-024 ENSP00000426261 ENST00000512389	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2273 aa 251.8 kDa	No	>9
CACNA1G-025 ENSP00000426232 ENST00000515765	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2321 aa 256.8 kDa	No	>9
CACNA1G-026 ENSP00000423317 ENST00000514079	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2291 aa 253.5 kDa	No	>9
CACNA1G-027 ENSP00000350979 ENST00000358244	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2171 aa 240.9 kDa	No	>9
CACNA1G-028 ENSP00000421518 ENST00000507896	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2194 aa 243.4 kDa	No	>9
CACNA1G-029 ENSP00000427697 ENST00000506520	H0YAN0 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006811 [ion transport] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] Show all	337 aa 37.5 kDa	No	4
CACNA1G-031 ENSP00000425522 ENST00000502264	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2306 aa 255 kDa	No	>9
CACNA1G-032 ENSP00000422268 ENST00000505165	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2205 aa 244.2 kDa	No	>9
CACNA1G-034 ENSP00000423155 ENST00000515411	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2314 aa 256 kDa	No	>9
CACNA1G-035 ENSP00000459988 ENST00000570567	I3L2W8 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005244 [voltage-gated ion channel activity] GO:0005886 [plasma membrane] GO:0006811 [ion transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0086010 [membrane depolarization during action potential] Show all	277 aa 31.5 kDa	No	5
CACNA1G-201 ENSP00000347078 ENST00000354983	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2343 aa 259.1 kDa	No	>9