Tissue expression of CACNA1G - Summary - The Human Protein Atlas

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CACNA1G

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CACNA1G
Gene description	Calcium channel, voltage-dependent, T type, alpha 1G subunit
Protein class	FDA approved drug targets Plasma proteins Predicted membrane proteins Voltage-gated ion channels
Predicted localization	Membrane
Number of transcripts	28
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (cerebral cortex, cervix, uterine)
GTEx:	Tissue enhanced (cerebellum)
FANTOM5:	Tissue enhanced (cerebellum)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results.
Reliability score	Uncertain based on 1 antibody. HPA004714
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

Skeletal muscle

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebral cortex, cervix, uterine)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebellum)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebellum)

GENE INFORMATION
Gene name	CACNA1G (HGNC Symbol)
Synonyms	Cav3.1, NBR13
Description	Calcium channel, voltage-dependent, T type, alpha 1G subunit (HGNC Symbol)
Entrez gene summary	Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]
Chromosome	17
Cytoband	q21.33
Chromosome location (bp)	50561068 - 50627474
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006283 (version 83.38)
Entrez gene	8913
UniProt	O43497 (UniProt - Evidence at transcript level)
neXtProt	NX_O43497
Antibodypedia	CACNA1G antibodies

PROTEIN BROWSER

CACNA1G-001	CACNA1G-002	CACNA1G-003	CACNA1G-004	CACNA1G-005	CACNA1G-007	CACNA1G-008	CACNA1G-009	CACNA1G-011	CACNA1G-013	CACNA1G-015	CACNA1G-016	CACNA1G-018	CACNA1G-019	CACNA1G-020	CACNA1G-021	CACNA1G-023	CACNA1G-024	CACNA1G-025	CACNA1G-026	CACNA1G-027	CACNA1G-028	CACNA1G-029	CACNA1G-031	CACNA1G-032	CACNA1G-034	CACNA1G-035	CACNA1G-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CACNA1G-001 ENSP00000339302 ENST00000352832	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2250 aa 249.3 kDa	No	>9
CACNA1G-002 ENSP00000425451 ENST00000513964	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2239 aa 247.8 kDa	No	>9
CACNA1G-003 ENSP00000422407 ENST00000514717	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2227 aa 246.2 kDa	No	>9
CACNA1G-004 ENSP00000426814 ENST00000510366	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2232 aa 247 kDa	No	>9
CACNA1G-005 ENSP00000427238 ENST00000503485	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2250 aa 248.7 kDa	No	>9
CACNA1G-007 ENSP00000414388 ENST00000429973	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2266 aa 251 kDa	No	>9
CACNA1G-008 ENSP00000353990 ENST00000360761	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2261 aa 250.2 kDa	No	>9
CACNA1G-009 ENSP00000423112 ENST00000507510	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2332 aa 257.7 kDa	No	>9
CACNA1G-011 ENSP00000420918 ENST00000507336	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2366 aa 261.6 kDa	No	>9
CACNA1G-013 ENSP00000352011 ENST00000359106	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0001508 [action potential] GO:0002027 [regulation of heart rate] GO:0005216 [ion channel activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007268 [synaptic transmission] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0010045 [response to nickel cation] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0060371 [regulation of atrial cardiac muscle cell membrane depolarization] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2377 aa 262.5 kDa	No	>9
CACNA1G-015 ENSP00000426172 ENST00000513689	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2287 aa 252.8 kDa	No	>9
CACNA1G-016 ENSP00000423045 ENST00000507609	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2277 aa 251.9 kDa	No	>9
CACNA1G-018 ENSP00000427173 ENST00000510115	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2298 aa 254.4 kDa	No	>9
CACNA1G-019 ENSP00000409759 ENST00000442258	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2243 aa 248.5 kDa	No	>9
CACNA1G-020 ENSP00000426098 ENST00000515165	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2284 aa 252.7 kDa	No	>9
CACNA1G-021 ENSP00000425698 ENST00000514181	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2259 aa 250.2 kDa	No	>9
CACNA1G-023 ENSP00000392390 ENST00000416767	A0A0B4J1X2 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006811 [ion transport] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] Show all	1555 aa 171.4 kDa	No	>9
CACNA1G-024 ENSP00000426261 ENST00000512389	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2273 aa 251.8 kDa	No	>9
CACNA1G-025 ENSP00000426232 ENST00000515765	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2321 aa 256.8 kDa	No	>9
CACNA1G-026 ENSP00000423317 ENST00000514079	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2291 aa 253.5 kDa	No	>9
CACNA1G-027 ENSP00000350979 ENST00000358244	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2171 aa 240.9 kDa	No	>9
CACNA1G-028 ENSP00000421518 ENST00000507896	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2194 aa 243.4 kDa	No	>9
CACNA1G-029 ENSP00000427697 ENST00000506520	H0YAN0 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006811 [ion transport] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] Show all	337 aa 37.5 kDa	No	4
CACNA1G-031 ENSP00000425522 ENST00000502264	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2306 aa 255 kDa	No	>9
CACNA1G-032 ENSP00000422268 ENST00000505165	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2205 aa 244.2 kDa	No	>9
CACNA1G-034 ENSP00000423155 ENST00000515411	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2314 aa 256 kDa	No	>9
CACNA1G-035 ENSP00000459988 ENST00000570567	I3L2W8 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005244 [voltage-gated ion channel activity] GO:0005886 [plasma membrane] GO:0006811 [ion transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0086010 [membrane depolarization during action potential] Show all	277 aa 31.5 kDa	No	5
CACNA1G-201 ENSP00000347078 ENST00000354983	O43497 [Direct mapping] Voltage-dependent T-type calcium channel subunit alpha-1G Show all	Voltage-gated ion channels Voltage-Gated Calcium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0005216 [ion channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007411 [axon guidance] GO:0008332 [low voltage-gated calcium channel activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0045956 [positive regulation of calcium ion-dependent exocytosis] GO:0055085 [transmembrane transport] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] GO:0097110 [scaffold protein binding] Show all	2343 aa 259.1 kDa	No	>9

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.