Tissue expression of TTC22 - Summary - The Human Protein Atlas

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TTC22

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TTC22
Gene description	Tetratricopeptide repeat domain 22
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (esophagus)
GTEx:	Tissue enhanced (esophagus, vagina)
FANTOM5:	Tissue enhanced (esophagus, small intestine)

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA035072
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (esophagus)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (esophagus, vagina)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (esophagus, small intestine)

GENE INFORMATION
Gene name	TTC22 (HGNC Symbol)
Synonyms	FLJ20619
Description	Tetratricopeptide repeat domain 22 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein with seven tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]
Chromosome	1
Cytoband	p32.3
Chromosome location (bp)	54779712 - 54801267
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006555 (version 83.38)
Entrez gene	55001
UniProt	Q5TAA0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5TAA0
Antibodypedia	TTC22 antibodies

PROTEIN BROWSER

TTC22-001	TTC22-002	TTC22-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TTC22-001 ENSP00000360321 ENST00000371274	Q5TAA0 [Direct mapping] Tetratricopeptide repeat protein 22 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	372 aa 41.8 kDa	No	0
TTC22-002 ENSP00000360323 ENST00000371276	Q5TAA0 [Direct mapping] Tetratricopeptide repeat protein 22 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	569 aa 63.4 kDa	No	0
TTC22-003 ENSP00000390300 ENST00000448308	H0Y486 [Direct mapping] Tetratricopeptide repeat protein 22 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		170 aa 19.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.