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BAZ1B

GENERAL INFORMATION

Gene name

 BAZ1B

Gene description

 Bromodomain adjacent to zinc finger domain, 1B

Protein class

 Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Supported based on 2 antibodies.
CAB037081 , CAB037158
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 BAZ1B (HGNC Symbol)

Synonyms

 WBSCR10, WBSCR9, WSTF

Description

 Bromodomain adjacent to zinc finger domain, 1B (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008]

Chromosome

 7

Cytoband

 q11.23

Chromosome location (bp)

 73440398 - 73522278

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000009954 (version 83.38)

Entrez gene

 9031

UniProt

 Q9UIG0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UIG0

Antibodypedia

 BAZ1B antibodies

PROTEIN BROWSER
BAZ1B-001
BAZ1B-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BAZ1B-001
ENSP00000342434
ENST00000339594
Q9UIG0 [Direct mapping]
Tyrosine-protein kinase BAZ1B
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Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Plasma proteins
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000793 [condensed chromosome]
GO:0003007 [heart morphogenesis]
GO:0003682 [chromatin binding]
GO:0004713 [protein tyrosine kinase activity]
GO:0004715 [non-membrane spanning protein tyrosine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005721 [pericentric heterochromatin]
GO:0006281 [DNA repair]
GO:0006302 [double-strand break repair]
GO:0006333 [chromatin assembly or disassembly]
GO:0006338 [chromatin remodeling]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008270 [zinc ion binding]
GO:0016572 [histone phosphorylation]
GO:0018108 [peptidyl-tyrosine phosphorylation]
GO:0035173 [histone kinase activity]
GO:0042393 [histone binding]
GO:0043596 [nuclear replication fork]
GO:0048096 [chromatin-mediated maintenance of transcription]
GO:0070577 [lysine-acetylated histone binding]
GO:0071884 [vitamin D receptor activator activity]
GO:2000273 [positive regulation of receptor activity]
Show all
 1483 aa
170.9 kDa 		No 0
BAZ1B-002
ENSP00000385442
ENST00000404251
Q9UIG0 [Direct mapping]
Tyrosine-protein kinase BAZ1B
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Plasma proteins
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003007 [heart morphogenesis]
GO:0003682 [chromatin binding]
GO:0004713 [protein tyrosine kinase activity]
GO:0004715 [non-membrane spanning protein tyrosine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0006281 [DNA repair]
GO:0006302 [double-strand break repair]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008270 [zinc ion binding]
GO:0016572 [histone phosphorylation]
GO:0018108 [peptidyl-tyrosine phosphorylation]
GO:0035173 [histone kinase activity]
GO:0043596 [nuclear replication fork]
GO:0048096 [chromatin-mediated maintenance of transcription]
GO:0070577 [lysine-acetylated histone binding]
Show all
 1483 aa
170.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.