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RANBP9

GENERAL INFORMATION

Gene name

 RANBP9

Gene description

 RAN binding protein 9

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General nuclear and cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA050007 , CAB033767
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PROGNOSTIC SUMMARY
Prognostic marker in ovarian cancer (favourable) and head and neck cancer (favourable).
Ovarian cancer p<0.001
Head and neck cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA050007
CAB033767

GENE INFORMATION

Gene name

 RANBP9 (HGNC Symbol)

Synonyms

 RanBPM

Description

 RAN binding protein 9 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]

Chromosome

 6

Cytoband

 p23

Chromosome location (bp)

 13621498 - 13711564

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000010017 (version 83.38)

Entrez gene

 10048

UniProt

 Q96S59 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96S59

Antibodypedia

 RANBP9 antibodies

PROTEIN BROWSER
RANBP9-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RANBP9-001
ENSP00000011619
ENST00000011619
Q96S59 [Direct mapping]
Ran-binding protein 9
A0A024QZW3 [Target identity:100%; Query identity:100%]
RAN binding protein 9, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005875 [microtubule associated complex]
GO:0006461 [protein complex assembly]
GO:0007020 [microtubule nucleation]
GO:0007411 [axon guidance]
GO:0008536 [Ran GTPase binding]
GO:0019899 [enzyme binding]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
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 729 aa
77.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.