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MRI1

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GENERAL INFORMATION

Gene name

 MRI1

Gene description

 Methylthioribose-1-phosphate isomerase 1

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the cytosol, nucleoli (fibrillar center) & nucleoplasm.

RNA cell category

 Mixed

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (supported), Nucleoli fibrillar center (supported), Cytosol (supported)

Single-cell variation

 Single-cell variation in protein expression observed.

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA042744
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the cytosol, nucleoli (fibrillar center) & nucleoplasm.

Main location

 Nucleoplasm (supported), Nucleoli fibrillar center (supported), Cytosol (supported)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA042744 A-431 Nucleoplasm
Cytosol
HPA042744 U-2 OS Nucleoplasm
Cytosol
HPA042744 U-251 MG Nucleoplasm
Nucleoli fibrillar center Intensity
Cytosol

GENE INFORMATION

Gene name

 MRI1 (HGNC Symbol)

Synonyms

 MGC3207, MRDI, mtnA, Ypr118w

Description

 Methylthioribose-1-phosphate isomerase 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.13

Chromosome location (bp)

 13764532 - 13774282

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000037757 (version 83.38)

Entrez gene

 84245

UniProt

 Q9BV20 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BV20

Antibodypedia

 MRI1 antibodies

PROTEIN BROWSER
MRI1-001
MRI1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MRI1-001
ENSP00000314871
ENST00000319545
Q9BV20 [Direct mapping]
Methylthioribose-1-phosphate isomerase
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Enzymes
   ENZYME proteins
   Isomerase
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000096 [sulfur amino acid metabolic process]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006595 [polyamine metabolic process]
GO:0019284 [L-methionine biosynthetic process from S-adenosylmethionine]
GO:0019509 [L-methionine biosynthetic process from methylthioadenosine]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0042802 [identical protein binding]
GO:0042995 [cell projection]
GO:0044237 [cellular metabolic process]
GO:0044249 [cellular biosynthetic process]
GO:0044281 [small molecule metabolic process]
GO:0046523 [S-methyl-5-thioribose-1-phosphate isomerase activity]
Show all
 322 aa
34.5 kDa 		No 0
MRI1-002
ENSP00000040663
ENST00000040663
Q9BV20 [Direct mapping]
Methylthioribose-1-phosphate isomerase
Show all
Enzymes
   ENZYME proteins
   Isomerase
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000096 [sulfur amino acid metabolic process]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006595 [polyamine metabolic process]
GO:0019284 [L-methionine biosynthetic process from S-adenosylmethionine]
GO:0019509 [L-methionine biosynthetic process from methylthioadenosine]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0042802 [identical protein binding]
GO:0042995 [cell projection]
GO:0044237 [cellular metabolic process]
GO:0044249 [cellular biosynthetic process]
GO:0044281 [small molecule metabolic process]
GO:0046523 [S-methyl-5-thioribose-1-phosphate isomerase activity]
Show all
 369 aa
39.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.