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MRI1

GENERAL INFORMATION

Gene name

 MRI1

Gene description

 Methylthioribose-1-phosphate isomerase 1

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General cytoplasmic and nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA042744 , CAB045988
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA042744
CAB045988

GENE INFORMATION

Gene name

 MRI1 (HGNC Symbol)

Synonyms

 MGC3207, MRDI, mtnA, Ypr118w

Description

 Methylthioribose-1-phosphate isomerase 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.13

Chromosome location (bp)

 13764532 - 13774282

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000037757 (version 83.38)

Entrez gene

 84245

UniProt

 Q9BV20 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BV20

Antibodypedia

 MRI1 antibodies

PROTEIN BROWSER
MRI1-001
MRI1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MRI1-001
ENSP00000314871
ENST00000319545
Q9BV20 [Direct mapping]
Methylthioribose-1-phosphate isomerase
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Enzymes
   ENZYME proteins
   Isomerase
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000096 [sulfur amino acid metabolic process]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006595 [polyamine metabolic process]
GO:0019284 [L-methionine biosynthetic process from S-adenosylmethionine]
GO:0019509 [L-methionine biosynthetic process from methylthioadenosine]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0042802 [identical protein binding]
GO:0042995 [cell projection]
GO:0044237 [cellular metabolic process]
GO:0044249 [cellular biosynthetic process]
GO:0044281 [small molecule metabolic process]
GO:0046523 [S-methyl-5-thioribose-1-phosphate isomerase activity]
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 322 aa
34.5 kDa 		No 0
MRI1-002
ENSP00000040663
ENST00000040663
Q9BV20 [Direct mapping]
Methylthioribose-1-phosphate isomerase
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Enzymes
   ENZYME proteins
   Isomerase
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000096 [sulfur amino acid metabolic process]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006595 [polyamine metabolic process]
GO:0019284 [L-methionine biosynthetic process from S-adenosylmethionine]
GO:0019509 [L-methionine biosynthetic process from methylthioadenosine]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0042802 [identical protein binding]
GO:0042995 [cell projection]
GO:0044237 [cellular metabolic process]
GO:0044249 [cellular biosynthetic process]
GO:0044281 [small molecule metabolic process]
GO:0046523 [S-methyl-5-thioribose-1-phosphate isomerase activity]
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 369 aa
39.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.