Expression of NOP16 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

NOP16

TISSUE

premium

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	NOP16
Gene description	NOP16 nucleolar protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nucleolar staining at variable levels in all tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA036506
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036506

GENE INFORMATION
Gene name	NOP16 (HGNC Symbol)
Synonyms	HSPC111, HSPC185, LOC51491
Description	NOP16 nucleolar protein (HGNC Symbol)
Entrez gene summary	NOP16 is transcriptionally regulated by c-Myc (MYC; MIM 190080), upregulated in breast cancer, and overexpression is associated with poor patient survival (Butt et al., 2008).[supplied by OMIM, Jun 2009]
Chromosome	5
Cytoband	q35.2
Chromosome location (bp)	176383938 - 176388975
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000048162 (version 83.38)
Entrez gene	51491
UniProt	Q9Y3C1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y3C1
Antibodypedia	NOP16 antibodies

PROTEIN BROWSER

NOP16-001	NOP16-002	NOP16-008	NOP16-009	NOP16-201	NOP16-202	NOP16-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NOP16-001 ENSP00000480832 ENST00000614830	Q9Y3C1 [Direct mapping] Nucleolar protein 16 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0042273 [ribosomal large subunit biogenesis] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] Show all	178 aa 21.2 kDa	No	0
NOP16-002 ENSP00000479445 ENST00000621444	A0A0C4DGU5 [Direct mapping] Nucleolar protein 16 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0042273 [ribosomal large subunit biogenesis] Show all	231 aa 26.4 kDa	No	0
NOP16-008 ENSP00000478283 ENST00000616685	A0A087WU10 [Direct mapping] Nucleolar protein 16 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0042273 [ribosomal large subunit biogenesis] Show all	70 aa 8.1 kDa	No	0
NOP16-009 ENSP00000427489 ENST00000509257	D6RIC3 [Direct mapping] Nucleolar protein 16 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0042273 [ribosomal large subunit biogenesis] GO:0043231 [intracellular membrane-bounded organelle] Show all	150 aa 17.2 kDa	No	0
NOP16-201 ENSP00000484440 ENST00000613081	A0A087X1T1 [Direct mapping] Nucleolar protein 16 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0042273 [ribosomal large subunit biogenesis] Show all	236 aa 26.9 kDa	No	0
NOP16-202 ENSP00000483001 ENST00000618911	Q9Y3C1 [Direct mapping] Nucleolar protein 16 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0042273 [ribosomal large subunit biogenesis] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] Show all	232 aa 26.6 kDa	No	0
NOP16-203 ENSP00000484969 ENST00000619979	A0A087X2G6 [Direct mapping] Nucleolar protein 16 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0042273 [ribosomal large subunit biogenesis] Show all	237 aa 27.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.