Tissue expression of TNFRSF17 - Summary

GENERAL INFORMATION
Gene name	TNFRSF17
Gene description	Tumor necrosis factor receptor superfamily, member 17
Protein class	Cancer-related genes CD markers Disease related genes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (tonsil)
GTEx:	Tissue enhanced (spleen)
FANTOM5:	Tissue enhanced (appendix, tonsil)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (tonsil)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (spleen)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (appendix, tonsil)

GENE INFORMATION
Gene name	TNFRSF17 (HGNC Symbol)
Synonyms	BCM, BCMA, CD269, TNFRSF13A
Description	Tumor necrosis factor receptor superfamily, member 17 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
Chromosome	16
Cytoband	p13.13
Chromosome location (bp)	11965107 - 11968068
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000048462 (version 83.38)
Entrez gene	608
UniProt	Q02223 (UniProt - Evidence at protein level)
neXtProt	NX_Q02223
Antibodypedia	TNFRSF17 antibodies

PROTEIN BROWSER

TNFRSF17-001	TNFRSF17-002	TNFRSF17-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TNFRSF17-001 ENSP00000053243 ENST00000053243	Q02223 [Direct mapping] Tumor necrosis factor receptor superfamily member 17 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Show all	GO:0002250 [adaptive immune response] GO:0002260 [lymphocyte homeostasis] GO:0004872 [receptor activity] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0008283 [cell proliferation] GO:0012505 [endomembrane system] GO:0016021 [integral component of membrane] GO:0033209 [tumor necrosis factor-mediated signaling pathway] Show all	184 aa 20.2 kDa	No	1
TNFRSF17-002 ENSP00000454314 ENST00000562385	H3BMB5 [Direct mapping] Tumor necrosis factor receptor superfamily member 17 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0016021 [integral component of membrane] Show all	133 aa 14.9 kDa	No	1
TNFRSF17-003 ENSP00000379753 ENST00000396495	Q02223 [Direct mapping] Tumor necrosis factor receptor superfamily member 17 Show all	CD markers Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Show all	GO:0002250 [adaptive immune response] GO:0004872 [receptor activity] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0008283 [cell proliferation] GO:0012505 [endomembrane system] GO:0016021 [integral component of membrane] GO:0033209 [tumor necrosis factor-mediated signaling pathway] Show all	135 aa 14.8 kDa	No	0