Tissue expression of CELF2 - Summary - The Human Protein Atlas

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CELF2

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TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CELF2
Gene description	CUGBP, Elav-like family member 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	12
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Selective expression in neuronal cells, bone marrow, lymphoid tissue with immune cells in several tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Caution, Splice and/or transcript discrepancy exists.
Reliability score	Supported based on 2 antibodies. HPA035813 , CAB016395
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CELF2 (HGNC Symbol)
Synonyms	BRUNOL3, CUGBP2, Etr-3, NAPOR-2
Description	CUGBP, Elav-like family member 2 (HGNC Symbol)
Entrez gene summary	Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	p14
Chromosome location (bp)	11005321 - 11336675
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000048740 (version 83.38)
Entrez gene	10659
UniProt	O95319 (UniProt - Evidence at protein level)
neXtProt	NX_O95319
Antibodypedia	CELF2 antibodies

PROTEIN BROWSER

CELF2-001	CELF2-002	CELF2-003	CELF2-004	CELF2-005	CELF2-007	CELF2-008	CELF2-010	CELF2-011	CELF2-012	CELF2-015	CELF2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CELF2-001 ENSP00000404834 ENST00000417956	O95319 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006396 [RNA processing] GO:0006397 [mRNA processing] GO:0008016 [regulation of heart contraction] GO:0044822 [poly(A) RNA binding] Show all	490 aa 52.3 kDa	No	0
CELF2-002 ENSP00000382743 ENST00000399850	O95319 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006396 [RNA processing] GO:0006397 [mRNA processing] GO:0008016 [regulation of heart contraction] GO:0044822 [poly(A) RNA binding] Show all	490 aa 52.3 kDa	No	0
CELF2-003 ENSP00000346971 ENST00000354897	Q5VZZ6 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] Show all	502 aa 53.7 kDa	No	0
CELF2-004 ENSP00000476999 ENST00000608830	O95319 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006396 [RNA processing] GO:0006397 [mRNA processing] GO:0008016 [regulation of heart contraction] GO:0044822 [poly(A) RNA binding] Show all	488 aa 52.1 kDa	No	0
CELF2-005 ENSP00000476656 ENST00000609692	V9GYD9 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] Show all	440 aa 46.6 kDa	No	0
CELF2-007 ENSP00000406451 ENST00000416382	O95319 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006396 [RNA processing] GO:0006397 [mRNA processing] GO:0008016 [regulation of heart contraction] GO:0044822 [poly(A) RNA binding] Show all	508 aa 54.3 kDa	No	0
CELF2-008 ENSP00000488582 ENST00000631460	O95319 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006396 [RNA processing] GO:0006397 [mRNA processing] GO:0008016 [regulation of heart contraction] GO:0044822 [poly(A) RNA binding] Show all	508 aa 54.3 kDa	No	0
CELF2-010 ENSP00000488268 ENST00000631816		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	514 aa 54.9 kDa	No	0
CELF2-011 ENSP00000488422 ENST00000632065		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	533 aa 57.1 kDa	No	0
CELF2-012 ENSP00000488690 ENST00000633077		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	521 aa 55.7 kDa	No	0
CELF2-015 ENSP00000487802 ENST00000632728	O95319 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006396 [RNA processing] GO:0006397 [mRNA processing] GO:0008016 [regulation of heart contraction] GO:0044822 [poly(A) RNA binding] Show all	490 aa 52.3 kDa	No	0
CELF2-201 ENSP00000443926 ENST00000542579	E9PC62 [Direct mapping] CUGBP Elav-like family member 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005737 [cytoplasm] GO:0006376 [mRNA splice site selection] Show all	521 aa 55.7 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.