Fields »
ABOUT
HELP
BLOG
NOP58

GENERAL INFORMATION

Gene name

 NOP58

Gene description

 NOP58 ribonucleoprotein

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Distinct expression in the nuclei and nucleoli in most cell types.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA018472 , HPA021062
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NOP58 (HGNC Symbol)

Synonyms

 HSPC120, NOP5

Description

 NOP58 ribonucleoprotein (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs. [provided by RefSeq, Nov 2015]

Chromosome

 2

Cytoband

 q33.1

Chromosome location (bp)

 202265716 - 202303666

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000055044 (version 83.38)

Entrez gene

 51602

UniProt

 Q9Y2X3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y2X3

Antibodypedia

 NOP58 antibodies

PROTEIN BROWSER
NOP58-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NOP58-001
ENSP00000264279
ENST00000264279
Q9Y2X3 [Direct mapping]
Nucleolar protein 58
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000154 [rRNA modification]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005732 [small nucleolar ribonucleoprotein complex]
GO:0005737 [cytoplasm]
GO:0006364 [rRNA processing]
GO:0006608 [snRNP protein import into nucleus]
GO:0015030 [Cajal body]
GO:0016020 [membrane]
GO:0016049 [cell growth]
GO:0030515 [snoRNA binding]
GO:0031428 [box C/D snoRNP complex]
GO:0032040 [small-subunit processome]
GO:0044822 [poly(A) RNA binding]
GO:0070761 [pre-snoRNP complex]
Show all
 529 aa
59.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.