Cell atlas - CYB5R4 - The Human Protein Atlas

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CYB5R4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CYB5R4
Gene description	Cytochrome b5 reductase 4
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CYB5R4 (HGNC Symbol)
Synonyms	b5+b5R, dJ676J13.1, NCB5OR
Description	Cytochrome b5 reductase 4 (HGNC Symbol)
Entrez gene summary	NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5 reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 [PubMed 10611283]).[supplied by OMIM, Jan 2010]
Chromosome	6
Cytoband	q14.2
Chromosome location (bp)	83859643 - 83967424
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000065615 (version 83.38)
Entrez gene	51167
UniProt	Q7L1T6 (UniProt - Evidence at protein level)
neXtProt	NX_Q7L1T6
Antibodypedia	CYB5R4 antibodies

PROTEIN BROWSER

CYB5R4-001	CYB5R4-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CYB5R4-001 ENSP00000358695 ENST00000369681	Q7L1T6 [Direct mapping] Cytochrome b5 reductase 4 Show all	Enzymes ENZYME proteins Oxidoreductases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003032 [detection of oxygen] GO:0003958 [NADPH-hemoprotein reductase activity] GO:0004128 [cytochrome-b5 reductase activity, acting on NAD(P)H] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0006091 [generation of precursor metabolites and energy] GO:0006739 [NADP metabolic process] GO:0006801 [superoxide metabolic process] GO:0016174 [NAD(P)H oxidase activity] GO:0016491 [oxidoreductase activity] GO:0016653 [oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor] GO:0020037 [heme binding] GO:0030073 [insulin secretion] GO:0042593 [glucose homeostasis] GO:0046677 [response to antibiotic] GO:0046872 [metal ion binding] GO:0048468 [cell development] GO:0048471 [perinuclear region of cytoplasm] GO:0050660 [flavin adenine dinucleotide binding] GO:0055114 [oxidation-reduction process] Show all	521 aa 59.5 kDa	No	0
CYB5R4-003 ENSP00000358693 ENST00000369679	A0A0A0MRM6 [Direct mapping] Cytochrome b5 reductase 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0020037 [heme binding] GO:0046872 [metal ion binding] Show all	109 aa 12.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.