Tissue expression of ZNRD1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ZNRD1
Gene description	Zinc ribbon domain containing 1
Protein class	Predicted intracellular proteins RNA polymerase related proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ZNRD1 (HGNC Symbol)
Synonyms	HTEX-6, hZR14, RPA12, tctex-6
Description	Zinc ribbon domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	30058899 - 30064909
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000066379 (version 83.38)
Entrez gene	30834
UniProt	Q9P1U0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9P1U0
Antibodypedia	ZNRD1 antibodies

PROTEIN BROWSER

ZNRD1-001	ZNRD1-002	ZNRD1-005	ZNRD1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNRD1-001 ENSP00000352333 ENST00000359374	Q9P1U0 [Direct mapping] DNA-directed RNA polymerase I subunit RPA12 Q2L6J2 [Target identity:100%; Query identity:100%] DNA-directed RNA polymerase subunit Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001054 [RNA polymerase I activity] GO:0003676 [nucleic acid binding] GO:0003899 [DNA-directed RNA polymerase activity] GO:0005654 [nucleoplasm] GO:0005736 [DNA-directed RNA polymerase I complex] GO:0006139 [nucleobase-containing compound metabolic process] GO:0006351 [transcription, DNA-templated] GO:0006360 [transcription from RNA polymerase I promoter] GO:0006361 [transcription initiation from RNA polymerase I promoter] GO:0006362 [transcription elongation from RNA polymerase I promoter] GO:0006363 [termination of RNA polymerase I transcription] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0040029 [regulation of gene expression, epigenetic] GO:0045814 [negative regulation of gene expression, epigenetic] Show all	126 aa 13.9 kDa	No	0
ZNRD1-002 ENSP00000331111 ENST00000332435	Q9P1U0 [Direct mapping] DNA-directed RNA polymerase I subunit RPA12 Q2L6J2 [Target identity:100%; Query identity:100%] DNA-directed RNA polymerase subunit Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001054 [RNA polymerase I activity] GO:0003676 [nucleic acid binding] GO:0003899 [DNA-directed RNA polymerase activity] GO:0005654 [nucleoplasm] GO:0005736 [DNA-directed RNA polymerase I complex] GO:0006139 [nucleobase-containing compound metabolic process] GO:0006351 [transcription, DNA-templated] GO:0006360 [transcription from RNA polymerase I promoter] GO:0006361 [transcription initiation from RNA polymerase I promoter] GO:0006362 [transcription elongation from RNA polymerase I promoter] GO:0006363 [termination of RNA polymerase I transcription] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0040029 [regulation of gene expression, epigenetic] GO:0045814 [negative regulation of gene expression, epigenetic] Show all	126 aa 13.9 kDa	No	0
ZNRD1-005 ENSP00000365978 ENST00000376782	Q9P1U0 [Direct mapping] DNA-directed RNA polymerase I subunit RPA12 Q2L6J2 [Target identity:100%; Query identity:100%] DNA-directed RNA polymerase subunit Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001054 [RNA polymerase I activity] GO:0003676 [nucleic acid binding] GO:0003899 [DNA-directed RNA polymerase activity] GO:0005654 [nucleoplasm] GO:0005736 [DNA-directed RNA polymerase I complex] GO:0006139 [nucleobase-containing compound metabolic process] GO:0006351 [transcription, DNA-templated] GO:0006360 [transcription from RNA polymerase I promoter] GO:0006361 [transcription initiation from RNA polymerase I promoter] GO:0006362 [transcription elongation from RNA polymerase I promoter] GO:0006363 [termination of RNA polymerase I transcription] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0040029 [regulation of gene expression, epigenetic] GO:0045814 [negative regulation of gene expression, epigenetic] Show all	126 aa 13.9 kDa	No	0
ZNRD1-006 ENSP00000365981 ENST00000376785	Q9P1U0 [Direct mapping] DNA-directed RNA polymerase I subunit RPA12 Q2L6J2 [Target identity:100%; Query identity:100%] DNA-directed RNA polymerase subunit Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001054 [RNA polymerase I activity] GO:0003676 [nucleic acid binding] GO:0003899 [DNA-directed RNA polymerase activity] GO:0005654 [nucleoplasm] GO:0005736 [DNA-directed RNA polymerase I complex] GO:0006139 [nucleobase-containing compound metabolic process] GO:0006351 [transcription, DNA-templated] GO:0006360 [transcription from RNA polymerase I promoter] GO:0006361 [transcription initiation from RNA polymerase I promoter] GO:0006362 [transcription elongation from RNA polymerase I promoter] GO:0006363 [termination of RNA polymerase I transcription] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0040029 [regulation of gene expression, epigenetic] GO:0045814 [negative regulation of gene expression, epigenetic] Show all	126 aa 13.9 kDa	No	0