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Term
Gene name

Class

Subclass

Chromosome

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In atlas

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Reliability

Reliability

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Validation

Method

Validation

Method

Validation

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Searches

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Cell line

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Detectable

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Detectable

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ZNRD1
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

ZNRD1

Gene description

Zinc ribbon domain containing 1

Protein class

Predicted intracellular proteins
RNA polymerase related proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY

Reliability score

Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW

Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

ZNRD1 (HGNC Symbol)

Synonyms

HTEX-6, hZR14, RPA12, tctex-6

Description

Zinc ribbon domain containing 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

6

Cytoband

p22.1

Chromosome location (bp)

30058899 - 30064909

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000066379 (version 83.38)

Entrez gene

30834

UniProt

Q9P1U0 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9P1U0

Antibodypedia

ZNRD1 antibodies

PROTEIN BROWSER

ZNRD1-001
ZNRD1-002
ZNRD1-005
ZNRD1-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZNRD1-001
ENSP00000352333
ENST00000359374
Q9P1U0 [Direct mapping]
DNA-directed RNA polymerase I subunit RPA12
Q2L6J2 [Target identity:100%; Query identity:100%]
DNA-directed RNA polymerase subunit
Show all
Predicted intracellular proteins
RNA polymerase related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001054 [RNA polymerase I activity]
GO:0003676 [nucleic acid binding]
GO:0003899 [DNA-directed RNA polymerase activity]
GO:0005654 [nucleoplasm]
GO:0005736 [DNA-directed RNA polymerase I complex]
GO:0006139 [nucleobase-containing compound metabolic process]
GO:0006351 [transcription, DNA-templated]
GO:0006360 [transcription from RNA polymerase I promoter]
GO:0006361 [transcription initiation from RNA polymerase I promoter]
GO:0006362 [transcription elongation from RNA polymerase I promoter]
GO:0006363 [termination of RNA polymerase I transcription]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0040029 [regulation of gene expression, epigenetic]
GO:0045814 [negative regulation of gene expression, epigenetic]
Show all
126 aa
13.9 kDa
No 0
ZNRD1-002
ENSP00000331111
ENST00000332435
Q9P1U0 [Direct mapping]
DNA-directed RNA polymerase I subunit RPA12
Q2L6J2 [Target identity:100%; Query identity:100%]
DNA-directed RNA polymerase subunit
Show all
Predicted intracellular proteins
RNA polymerase related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001054 [RNA polymerase I activity]
GO:0003676 [nucleic acid binding]
GO:0003899 [DNA-directed RNA polymerase activity]
GO:0005654 [nucleoplasm]
GO:0005736 [DNA-directed RNA polymerase I complex]
GO:0006139 [nucleobase-containing compound metabolic process]
GO:0006351 [transcription, DNA-templated]
GO:0006360 [transcription from RNA polymerase I promoter]
GO:0006361 [transcription initiation from RNA polymerase I promoter]
GO:0006362 [transcription elongation from RNA polymerase I promoter]
GO:0006363 [termination of RNA polymerase I transcription]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0040029 [regulation of gene expression, epigenetic]
GO:0045814 [negative regulation of gene expression, epigenetic]
Show all
126 aa
13.9 kDa
No 0
ZNRD1-005
ENSP00000365978
ENST00000376782
Q9P1U0 [Direct mapping]
DNA-directed RNA polymerase I subunit RPA12
Q2L6J2 [Target identity:100%; Query identity:100%]
DNA-directed RNA polymerase subunit
Show all
Predicted intracellular proteins
RNA polymerase related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001054 [RNA polymerase I activity]
GO:0003676 [nucleic acid binding]
GO:0003899 [DNA-directed RNA polymerase activity]
GO:0005654 [nucleoplasm]
GO:0005736 [DNA-directed RNA polymerase I complex]
GO:0006139 [nucleobase-containing compound metabolic process]
GO:0006351 [transcription, DNA-templated]
GO:0006360 [transcription from RNA polymerase I promoter]
GO:0006361 [transcription initiation from RNA polymerase I promoter]
GO:0006362 [transcription elongation from RNA polymerase I promoter]
GO:0006363 [termination of RNA polymerase I transcription]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0040029 [regulation of gene expression, epigenetic]
GO:0045814 [negative regulation of gene expression, epigenetic]
Show all
126 aa
13.9 kDa
No 0
ZNRD1-006
ENSP00000365981
ENST00000376785
Q9P1U0 [Direct mapping]
DNA-directed RNA polymerase I subunit RPA12
Q2L6J2 [Target identity:100%; Query identity:100%]
DNA-directed RNA polymerase subunit
Show all
Predicted intracellular proteins
RNA polymerase related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001054 [RNA polymerase I activity]
GO:0003676 [nucleic acid binding]
GO:0003899 [DNA-directed RNA polymerase activity]
GO:0005654 [nucleoplasm]
GO:0005736 [DNA-directed RNA polymerase I complex]
GO:0006139 [nucleobase-containing compound metabolic process]
GO:0006351 [transcription, DNA-templated]
GO:0006360 [transcription from RNA polymerase I promoter]
GO:0006361 [transcription initiation from RNA polymerase I promoter]
GO:0006362 [transcription elongation from RNA polymerase I promoter]
GO:0006363 [termination of RNA polymerase I transcription]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0040029 [regulation of gene expression, epigenetic]
GO:0045814 [negative regulation of gene expression, epigenetic]
Show all
126 aa
13.9 kDa
No 0

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