Cell atlas - IDI1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

IDI1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	IDI1
Gene description	Isopentenyl-diphosphate delta isomerase 1
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	IDI1
Synonyms
Description	Isopentenyl-diphosphate delta isomerase 1 (HGNC Symbol)
Entrez gene summary	IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	p15.3
Chromosome location (bp)	1039908 - 1049170
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000067064 (version 83.38)
Entrez gene	3422
UniProt	Q13907 (UniProt - Evidence at protein level)
neXtProt	NX_Q13907
Antibodypedia	IDI1 antibodies

PROTEIN BROWSER

IDI1-002	IDI1-003	IDI1-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IDI1-002 ENSP00000401879 ENST00000429642	C9JKM8 [Direct mapping] Isopentenyl-diphosphate Delta-isomerase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004452 [isopentenyl-diphosphate delta-isomerase activity] GO:0008299 [isoprenoid biosynthetic process] GO:0016787 [hydrolase activity] Show all	122 aa 13.8 kDa	No	0
IDI1-003 ENSP00000404771 ENST00000427898	C9JD53 [Direct mapping] Isopentenyl-diphosphate Delta-isomerase 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004452 [isopentenyl-diphosphate delta-isomerase activity] GO:0008299 [isoprenoid biosynthetic process] GO:0016787 [hydrolase activity] Show all	120 aa 13.7 kDa	No	0
IDI1-004 ENSP00000370748 ENST00000381344	Q13907 [Direct mapping] Isopentenyl-diphosphate Delta-isomerase 1 Show all	Enzymes ENZYME proteins Isomerase Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004452 [isopentenyl-diphosphate delta-isomerase activity] GO:0005777 [peroxisome] GO:0005829 [cytosol] GO:0006695 [cholesterol biosynthetic process] GO:0008299 [isoprenoid biosynthetic process] GO:0016787 [hydrolase activity] GO:0030145 [manganese ion binding] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0050992 [dimethylallyl diphosphate biosynthetic process] Show all	284 aa 32.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.