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DNTTIP2

GENERAL INFORMATION

Gene name

 DNTTIP2

Gene description

 Deoxynucleotidyltransferase, terminal, interacting protein 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nucleolar expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA044502 , HPA053707
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 DNTTIP2 (HGNC Symbol)

Synonyms

 ERBP, HSU15552, TdIF2

Description

 Deoxynucleotidyltransferase, terminal, interacting protein 2 (HGNC Symbol)

Entrez gene summary

 This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010]

Chromosome

 1

Cytoband

 p22.1

Chromosome location (bp)

 93866283 - 93879918

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000067334 (version 83.38)

Entrez gene

 30836

UniProt

 Q5QJE6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5QJE6

Antibodypedia

 DNTTIP2 antibodies

PROTEIN BROWSER
DNTTIP2-001
DNTTIP2-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DNTTIP2-001
ENSP00000411010
ENST00000436063
Q5QJE6 [Direct mapping]
Deoxynucleotidyltransferase terminal-interacting protein 2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0044822 [poly(A) RNA binding]
Show all
 756 aa
84.5 kDa 		No 0
DNTTIP2-008
ENSP00000434261
ENST00000528680
E9PRB3 [Direct mapping]
Deoxynucleotidyltransferase terminal-interacting protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 161 aa
17.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.