Tissue expression of ATP11A - Summary - The Human Protein Atlas

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ATP11A

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ATP11A
Gene description	ATPase, class VI, type 11A
Protein class	Enzymes Plasma proteins Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Membranous and cytoplasmic expression in several tissues, including kidney.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 2 antibodies. HPA035583 , HPA035584
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

N/A

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ATP11A (HGNC Symbol)
Synonyms	ATPIH, ATPIS, KIAA1021
Description	ATPase, class VI, type 11A (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an integral membrane ATPase. The encoded protein is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium across membranes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	13
Cytoband	q34
Chromosome location (bp)	112690329 - 112887168
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000068650 (version 83.38)
Entrez gene	23250
UniProt	P98196 (UniProt - Evidence at protein level)
neXtProt	NX_P98196
Antibodypedia	ATP11A antibodies

PROTEIN BROWSER

ATP11A-001	ATP11A-003	ATP11A-004	ATP11A-010	ATP11A-014	ATP11A-201	ATP11A-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATP11A-001 ENSP00000420387 ENST00000487903	P98196 [Direct mapping] Probable phospholipid-transporting ATPase IH Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005765 [lysosomal membrane] GO:0005769 [early endosome] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0015914 [phospholipid transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0043231 [intracellular membrane-bounded organelle] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] GO:0055037 [recycling endosome] Show all	1134 aa 129.8 kDa	No	>9
ATP11A-003 ENSP00000396374 ENST00000418678	H0Y547 [Direct mapping] Phospholipid-transporting ATPase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0015914 [phospholipid transport] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] Show all	935 aa 106.5 kDa	No	6
ATP11A-004 ENSP00000410824 ENST00000419631	A2A3G9 [Direct mapping] Probable phospholipid-transporting ATPase IH Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] Show all	183 aa 20.7 kDa	No	2
ATP11A-010 ENSP00000402575 ENST00000415301	H0Y624 [Direct mapping] Probable phospholipid-transporting ATPase IH Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] Show all	75 aa 8.3 kDa	No	0
ATP11A-014 ENSP00000479392 ENST00000610419	A0A087WVE8 [Direct mapping] Probable phospholipid-transporting ATPase IH Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] Show all	62 aa 6.9 kDa	No	0
ATP11A-201 ENSP00000364781 ENST00000375630	E9PEJ6 [Direct mapping] Phospholipid-transporting ATPase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0015914 [phospholipid transport] GO:0016021 [integral component of membrane] GO:0043231 [intracellular membrane-bounded organelle] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] Show all	1191 aa 135.8 kDa	No	>9
ATP11A-202 ENSP00000364796 ENST00000375645	P98196 [Direct mapping] Probable phospholipid-transporting ATPase IH Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005765 [lysosomal membrane] GO:0005769 [early endosome] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0015914 [phospholipid transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0043231 [intracellular membrane-bounded organelle] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] GO:0055037 [recycling endosome] Show all	1134 aa 129.8 kDa	No	>9

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The Human Protein Atlas

The Human Protein Atlas project is funded
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