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Strong membranous immunoreactivity was observed in few hepatocellular carcinomas while few renal cancers exhibited moderate to strong cytoplasmic and/or membranous positivity. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
SCARB1 (HGNC Symbol)
Synonyms
CD36L1, CLA-1, CLA1, SR-BI, SRB1
Description
Scavenger receptor class B, member 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Q8WTV0 [Direct mapping] Scavenger receptor class B member 1 A0A024RBS4 [Target identity:100%; Query identity:100%] Scavenger receptor class B, member 1, isoform CRA_b
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Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)