Cell atlas - TUBA3D - The Human Protein Atlas

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TUBA3D

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Microtubules

Human cell
	Microtubules

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GENERAL INFORMATION
Gene name	TUBA3D
Gene description	Tubulin, alpha 3d
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the microtubules. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Localized to the Microtubules (supported)

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA039247 , HPA043684
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the microtubules. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Microtubules (supported)


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Antibody	Cell line	Location
HPA039247	A-431	Microtubules
HPA039247	U-2 OS	Microtubules
HPA039247	U-251 MG	Microtubules
HPA043684	PC-3	Microtubules
HPA043684	U-2 OS	Microtubules
HPA043684	U-251 MG	Microtubules

GENE INFORMATION
Gene name	TUBA3D (HGNC Symbol)
Synonyms	H2-ALPHA
Description	Tubulin, alpha 3d (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the alpha tubulin family. Tubulin is a major component of microtubules, which are composed of alpha- and beta-tubulin heterodimers and microtubule-associated proteins in the cytoskeleton. Microtubules maintain cellular structure, function in intracellular transport, and play a role in spindle formation during mitosis. [provided by RefSeq, Oct 2011]
Chromosome	2
Cytoband	q21.1
Chromosome location (bp)	131476093 - 131482934
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000075886 (version 83.38)
Entrez gene	113457
UniProt	Q13748 (UniProt - Evidence at protein level)
neXtProt	NX_Q13748
Antibodypedia	TUBA3D antibodies

PROTEIN BROWSER

TUBA3D-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TUBA3D-001 ENSP00000326042 ENST00000321253	Q13748 [Direct mapping] Tubulin alpha-3C/D chain Q1ZYQ1 [Target identity:100%; Query identity:100%] Tubulin, alpha 2; Tubulin, alpha 2, isoform CRA_b; cDNA FLJ77591, highly similar to Homo sapiens tubulin, alpha 2 (TUBA2), transcript variant 1, mRNA Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003924 [GTPase activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0006457 [protein folding] GO:0007017 [microtubule-based process] GO:0043234 [protein complex] GO:0044267 [cellular protein metabolic process] GO:0051084 ['de novo' posttranslational protein folding] GO:0051258 [protein polymerization] Show all	450 aa 50 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.