Fields »
ABOUT
HELP
BLOG
TUBA3D

GENERAL INFORMATION

Gene name

 TUBA3D

Gene description

 Tubulin, alpha 3d

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 4 antibodies.
HPA039247 , HPA043684 , HPA063394 , CAB004972
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and breast cancer (favourable).
Renal cancer p<0.001
Breast cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA039247
HPA043684
HPA063394
CAB004972

GENE INFORMATION

Gene name

 TUBA3D (HGNC Symbol)

Synonyms

 H2-ALPHA

Description

 Tubulin, alpha 3d (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the alpha tubulin family. Tubulin is a major component of microtubules, which are composed of alpha- and beta-tubulin heterodimers and microtubule-associated proteins in the cytoskeleton. Microtubules maintain cellular structure, function in intracellular transport, and play a role in spindle formation during mitosis. [provided by RefSeq, Oct 2011]

Chromosome

 2

Cytoband

 q21.1

Chromosome location (bp)

 131476093 - 131482934

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000075886 (version 83.38)

Entrez gene

 113457

UniProt

 Q13748 (UniProt - Evidence at protein level)

neXtProt

 NX_Q13748

Antibodypedia

 TUBA3D antibodies

PROTEIN BROWSER
TUBA3D-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TUBA3D-001
ENSP00000326042
ENST00000321253
Q13748 [Direct mapping]
Tubulin alpha-3C/D chain
Q1ZYQ1 [Target identity:100%; Query identity:100%]
Tubulin, alpha 2; Tubulin, alpha 2, isoform CRA_b; cDNA FLJ77591, highly similar to Homo sapiens tubulin, alpha 2 (TUBA2), transcript variant 1, mRNA
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0006457 [protein folding]
GO:0007017 [microtubule-based process]
GO:0043234 [protein complex]
GO:0044267 [cellular protein metabolic process]
GO:0051084 ['de novo' posttranslational protein folding]
GO:0051258 [protein polymerization]
Show all
 450 aa
50 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.